LY 171883, a CysLT1 Receptor (leukotriene D4) antagonist, has been shown to displace oleic acid binding to fatty-acid-binding protein (FABP) which may be involved in fatty acid metabolism. Studies suggest that this compound contains structural similarity to fatty acids, hence the ability to bind to FABPs. Additional data suggests that LY 171883 causes membrane hyperpolarization and reduces firing rate of action potentials in neuroblastoma cells|in vitro|. LY 171883 is an inhibitor of PDE and an activator of PPAR α and PPAR γ.
Molecular Formula: C16H22N4O3
Molecular Weight: 318.37
PubChem CID: 3969
Isomeric SMILES: CCCC1=C(C=CC(=C1O)C(=O)C)OCCCCC2=NNN=N2
Beilstein Registry Number: 4238438
Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/L331358-SCI_caa5c04aa1be632e9c8d19276fea3e10.pdf
- UPC:
- 42161635
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- L331358-10mg
- CAS:
- 88107-10-2
- Product Size:
- 10mg
- Hazard Statement Codes:
- H302
- Precautionary Statement Codes:
- P501:P301+P312:P330:P270:P264
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