InformationLu-135252 (Darusentan, HMR-4005) is a selective endothelin A (ETA) receptor antagonist. Darusentan competes for radiolabeled endothelin binding in rat aortic vascular smooth muscle cells (RAVSMs) membranes with single-site kinetics with Ki of 13 nM.
Specifications and Purity: ≥98%
Molecular Formula: C22H22N2O6
Molecular Weight: 410.43
PubChem CID: 177236
Isomeric SMILES: COC1=CC(=NC(=N1)O[C@H](C(=O)O)C(C2=CC=CC=C2)(C3=CC=CC=C3)OC)OC
Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/L412123-SCI_00a33b04623aa7df107f216d1cbcace8.pdf
- UPC:
- 41115309
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- L412123-5mg
- CAS:
- 171714-84-4
- Product Size:
- 5mg
- Hazard Statement Codes:
- H335:H319:H315:H302
- Precautionary Statement Codes:
- P305+P351+P338:P261
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