Biochem/physiol Actions
Losmapimod is a potent and selective inhibitor of the p38 mitogen-activated protein kinases (MAPK) family. In SHR-SP rats losmapimod improves survival, endothelial-dependent and -independent vascular relaxation. Also losmapimod attenuates dyslipidemia, hypertension, cardiac remodeling, plasma renin activity (PRA), aldosterone, and interleukin-1 (IL-1 ). Losmapimod produces antidepressant and antipsychotic effects.
- UPC:
- 51241110
- Condition:
- New
- HazmatClass:
- No
- MPN:
- SML3596-50MG
- CAS:
- 585543-15-3
akash.verma@cenmed.com
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