Application
Lorglumide sodium salt has been used as a cck-a (cholecystokinin A) receptor antagonist for peptide determination in rat islet cells. It has been used as a CCK1 inhibitor to check the effect of cck1 (cck-a) and cck2 (cck-b) receptors on cerulein-induced upregulation of egr-1 (early growth response 1) expression in rat pancreatic acinar cells.
Biochem/physiol Actions
Potent and selective non-peptide cholecystokinin (CCKA) receptor antagonist; orally active.
Molecular Weight: 481.39. Empirical Formula: C22H31Cl2N2NaO4. form: solid. Quality Level: 100. color: white. solubility: 45% (w/v) aq 2-hydroxypropyl-β. -cyclodextrin: >. 10 . mg/mL, H2O: 10 . mg/mL, methanol: 28 . mg/mL. SMILES string: [Na+].CCCCCN(CCCCC)C(: O)C(CCC([O-]): O)NC(: O)c1ccc(Cl)c(Cl)c1. InChI: 1S/C22H32Cl2N2O4.Na/c1-3-5-7-13-26(14-8-6-4-2)22(30)19(11-12-20(27)28)25-21(29)16-9-10-17(23)18(24)15-16. /h9-10,15,19H,3-8,11-14H2,1-2H3,(H,25,29)(H,27,28). /q. +1/p-1. InChI key: JCNPYMDDOUQTBK-UHFFFAOYSA-M. Gene Information: human ... CCKAR(886). Storage Class Code: 11 - Combustible Solids. WGK: WGK 2. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).- UPC:
- 51191602
- Condition:
- New
- HazmatClass:
- No
- MPN:
- L109-50MG
- CAS:
- 1021868-76-7
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