Lonafarnib-10 mg

Catalog No.: C003B-120346
Manufacturer No.: 11746-10
Manufacturer Name: CAYMAN CHEMICAL
Quantity: 1
Unit of Measure: EA

A farnesyl transferase inhibitor that blocks the post-translational lipid modification of oncogenic Ras isoforms H-Ras, N-Ras, and K-Ras (IC50s = 1.9, 2.

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Description
Specifications

A farnesyl transferase inhibitor that blocks the post-translational lipid modification of oncogenic Ras isoforms H-Ras, N-Ras, and K-Ras (IC50s = 1.9, 2.8, and 5.2 nM, respectively) and Rheb (IC50 = 10-100 nM); demonstrates potent dose-dependent oral activity in an array of human tumor xenograft models including tumors originating from colon, lung, pancreas, prostate, and urinary bladder.

UPC:: 51131507
Condition:: New
HazmatClass:: No"
WeightUOM:: LB
MPN:: 11746-10
Model Number:: C832J06
Temperature Control Device:: Yes
CAS:: 193275-84-2

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