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lly-507

LLY-507

Catalog No.
C005B-312315
Manufacturer No.
SML1279-5MG
Manufacturer Name
Sigma-Aldrich
Quantity
5
Unit of Measure
MG

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Biochem/physiol Actions LLY-507 is a potent and selective inhibitor of SMYD2 protein lysine methyltransferase (PKMT) with an in vitro IC 50 <:15 nM and >:100-fold selectivity over other methyltransferases and other non-epigenetic targets.

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Biochem/physiol Actions

LLY-507 is a potent and selective inhibitor of SMYD2 protein lysine methyltransferase (PKMT) with an in vitro IC50 <15 nM and >100-fold selectivity over other methyltransferases and other non-epigenetic targets. LY-507 has been shown to inhibit p53K370 monomethylation in cells with an IC50 ~600 nM. For full characterization details, please visit the LLY-507 probe summary on the Structural Genomics Consortium (SGC) website.

To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc

Features and Benefits

LLY-507 is an epigenetic chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC epigenetic probes, visit sigma.com/SGC.

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Other Notes

LLY-507 has been expertly reviewed and recommended by the Chemical Probes Portal. For more information, please visit the LLY-507 probe summary on the Chemical Probes Portal website.

UPC:
42152713
Condition:
New
HazmatClass:
No
MPN:
SML1279-5MG

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