Biochem/physiol Actions K03861 is an ATP site-binding, cyclin-competitive, type II CDK2 inhibitor that selectively targets and locks the kinase in its inactive DFG-out conformation (CDK2 Kd = 50 nM, DFG-out stabilizing CDK2-C118L/A144C mutant Kd =
Biochem/physiol Actions K03861 is an ATP site-binding, cyclin-competitive, type II CDK2 inhibitor that selectively targets and locks the kinase in its inactive DFG-out conformation (CDK2 Kd = 50 nM, DFG-out stabilizing CDK2-C118L/A144C mutant Kd =
Biochem/physiol Actions K03861 is an ATP site-binding, cyclin-competitive, type II CDK2 inhibitor that selectively targets and locks the kinase in its inactive DFG-out conformation (CDK2 Kd = 50 nM, DFG-out stabilizing CDK2-C118L/A144C mutant Kd =
Biochem/physiol Actions K03861 is an ATP site-binding, cyclin-competitive, type II CDK2 inhibitor that selectively targets and locks the kinase in its inactive DFG-out conformation (CDK2 Kd = 50 nM, DFG-out stabilizing CDK2-C118L/A144C mutant Kd =
KS106 is a potent ALDH inhibitor with IC 50 s of 334, 2137, 360 nM for ALDH1A1, ALDH2 , and ALDH3A1, respectively. KS106 shows antiproliferative and anticancer effects with low low toxic.KS106 significantly increases ROS activity, lipid peroxidation
KS106 is a potent ALDH inhibitor with IC 50 s of 334, 2137, 360 nM for ALDH1A1, ALDH2 , and ALDH3A1, respectively. KS106 shows antiproliferative and anticancer effects with low low toxic.KS106 significantly increases ROS activity, lipid peroxidation
KS106 is a potent ALDH inhibitor with IC 50 s of 334, 2137, 360 nM for ALDH1A1, ALDH2 , and ALDH3A1, respectively. KS106 shows antiproliferative and anticancer effects with low low toxic.KS106 significantly increases ROS activity, lipid peroxidation
KS106 is a potent ALDH inhibitor with IC 50 s of 334, 2137, 360 nM for ALDH1A1, ALDH2 , and ALDH3A1, respectively. KS106 shows antiproliferative and anticancer effects with low low toxic.KS106 significantly increases ROS activity, lipid peroxidation
KS106 is a potent ALDH inhibitor with IC 50 s of 334, 2137, 360 nM for ALDH1A1, ALDH2 , and ALDH3A1, respectively. KS106 shows antiproliferative and anticancer effects with low low toxic.KS106 significantly increases ROS activity, lipid peroxidation
KS106 is a potent ALDH inhibitor with IC 50 s of 334, 2137, 360 nM for ALDH1A1, ALDH2 , and ALDH3A1, respectively. KS106 shows antiproliferative and anticancer effects with low low toxic.KS106 significantly increases ROS activity, lipid peroxidation