LITHIUM BIS(TRIMETHYLSILYL)AMIDE 97% (C005B-038861)

General description

Lithium bis(trimethylsilyl)amide is a non-nucleophilic strong Brønsted base, which is generally soluble in most of the nonpolar organic solvents. It is most commonly employed in organic reactions.

Application

Base employed in generating enolates for the preparation of lactone precursors, pyranones, and cyclohexanes.
Used to catalyze the addition of phosphine P-H bonds to carbodiimides leading to phosphaguanidines. Also used in a novel three-step synthesis of disubstituted 1,2,5-thiadiazoles.

Molecular Weight: 167.33. Empirical Formula: C₆H₁₈LiNSi₂. linearFormula: [(CH₃)₃Si]₂NLi. Quality Level: 200. Assay: 97%. form: solid. density: 0.860 . g/mL . at 25 . °C (lit.). SMILES string: [Li]N([Si](C)(C)C)[Si](C)(C)C. InChI: 1S/C6H18NSi2.Li/c1-8(2,3)7-9(4,5)6. /h1-6H3. /q-1. +1. InChI key: YNESATAKKCNGOF-UHFFFAOYSA-N. Pictograms: GHS02,GHS05. Signal Word: Danger. Hazard Statements: H228 - H251 - H314. Precautionary Statements: P210 - P235 - P260 - P280 - P303 + P361 + P353 - P305 + P351 + P338. Hazard Classifications: Eye Dam. 1 - Flam. Sol. 1 - Self-heat. 1 - Skin Corr. 1B. Supp Hazards: EUH014. Storage Class Code: 4.2 - Pyrophoric and self-heating hazardous materials. WGK: WGK 2. Flash Point(F): 62.6 °F - closed cup. Flash Point(C): 17 °C - closed cup. Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges.