Lipofermata is a fatty acid transport protein 2 (FATP2) inhibitor. Lipofermata shows fatty acid transport inhibition with an IC 50 of 4.84 μM in Caco-2 cells. Lipofermata, an analog of spiro-indoline-thadiazole, shows zinc-specific suppression of antibacterial activity. Lipofermata perturbs zinc homeostasis in E. coli K-12 with a MIC of 16 μM .In VitroLipofermata inhibits C1-BODIPY-C12 transport into C2C12, INS-1E, Caco-2 and HepG2 cells at comparable levels yielding sigmoidal dose-response curves with IC 50 s in the low micromolar range (IC 50 =2.74-39.34 μM). MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Specifications and Purity: 10mM in DMSO
Molecular Formula: C15H10BrN3OS
Molecular Weight: 360.2
- UPC:
- 12352211
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- L655036-1ml
- CAS:
- 297180-15-5
- Product Size:
- 1ml
akash.verma@cenmed.com
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