Linoleoyl Ethanolamide-5 mg

Catalog No.: C003B-374349
Manufacturer No.: 90155-5
Manufacturer Name: CAYMAN CHEMICAL
Quantity: 1
Unit of Measure: EA

An endocannabinoid that contains linoleate in place of the arachidonate moiety of AEA has been detected in porcine brain and murine peritoneal macrophages and has weak affinity for the CB1 and CB2 receptors (Kis =10 µM and 25 µM,

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Description
Specifications

An endocannabinoid that contains linoleate in place of the arachidonate moiety of AEA; has been detected in porcine brain and murine peritoneal macrophages and has weak affinity for the CB1 and CB2 receptors (Kis =10 µM and 25 µM, respectively); 4-fold less potent than AEA at causing catalepsy in mice (ED50 = 26.5 mg/kg); increases ERK phosphorylation and AP-1-dependent transcription approximately 1.5 fold at 15 µM in a CB-receptor-independent manner; inhibits human FAAH-dependent hydrolysis of AEA (Ki = 9.0 µM), but is also effectively hydrolyzed by the enzyme.

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UPC:: 51142018
HazmatClass:: Yes
WeightUOM:: LB
MPN:: 90155-5

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