LINCOMYCIN HYDROCHLORIDE >= 95.0% (TLC) (C005B-082856)

General description

Chemical structure: macrolide

Biochem/physiol Actions

Mode of action: Lincomycin inhibits bacterial protein synthesis by forming cross-links within the peptidyl transferase loop region of the 23S rRNA.†

Antimicrobial spectrum: Lincomycin hydrochloride is effective against gram-positive bacteria.

Preparation Note

This product is soluble in water at 50 mg/mL, yielding a clear, colorless solution.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Molecular Weight: 443.00. Empirical Formula: C₁₈H₃₄N₂O₆S · HCl. Quality Level: 200. Assay: 96.0-102.0% (HPLC). form: powder or crystals. impurities: ≤. 5% water. color: white to off-white. solubility: H₂O: 50 . mg/mL, clear, colorless to faintly yellow. antibiotic activity spectrum: Gram-positive bacteria. Mode of action: protein synthesis | interferes. storage temp.: 2-8°C. SMILES string: Cl.CCC[C@@H]1C[C@H](N(C)C1)C(: O)N[C@H]([C@@H](C)O)[C@H]2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O. InChI: 1S/C18H34N2O6S.ClH/c1-5-6-10-7-11(20(3)8-10)17(25)19-12(9(2)21)16-14(23)13(22)15(24)18(26-16)27-4. /h9-16,18,21-24H,5-8H2,1-4H3,(H,19,25). 1H/t9-,10-,11+,12-,13+,14-,15-,16-,18-. /m1./s1. InChI key: POUMFISTNHIPTI-BOMBIWCESA-N. Pictograms: GHS07. Signal Word: Warning. Hazard Statements: H315 - H319 - H335. Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338. Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3. Target Organs: Respiratory system. Storage Class Code: 11 - Combustible Solids. WGK: WGK 2. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves.