LEFLUNOMIDE (C005B-456241)

Catalog No.: C005B-456241
Manufacturer No.: L5025-100MG
Manufacturer Name: Sigma-Aldrich
Quantity: 100
Unit of Measure: MG

Application By virtue of its immunosuppressant effects, leflunomide has found use in organ transplantation and treatment of rheumatoid arthritis and other autoimmune diseases. Biochem/physiol Actions Immunosuppressive: inhibits T and B cell

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Description
Specifications

Application

By virtue of its immunosuppressant effects, leflunomide has found use in organ transplantation and treatment of rheumatoid arthritis and other autoimmune diseases.

Biochem/physiol Actions

Immunosuppressive; inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is believed to inhibit dihydroorotate dehydrogenase (in the de novo pyrimidine synthesis pathway) as well as several protein tyrosine kinases.

UPC:: 51131507
Condition:: New
HazmatClass:: Yes
MPN:: L5025-100MG
CAS:: 75706-12-6

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