Lauric acid leelamide is the lauric (C-12) amide analog of leelamine. Leelamine has weak affinity for the human CB1 and CB2 receptors, exhibiting 20% displacement of [3H]-CP55940 at a concentration of 10 µM. Leelamine inhibits PDK with an IC50 value of 9.5 µM. Derivatives of leelamine exhibit anti-inflammatory activity and show moderate inhibition of PLA2 activity from a variety of sources. There are no published studies of the pharmacological properties of lauric acid leelamide.
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