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latrunculin a

LATRUNCULIN A FROM SEA SPONGE >=85% (HPLC) WAXY SOLID

Catalog No.
C005B-456184
Manufacturer No.
L5163-100UG
Manufacturer Name
Sigma-Aldrich
Quantity
1
Unit of Measure
EA

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General description Latrunculin A, a toxin extracted from the red sea sponge Latrunculia magnifica . It participates in vitro in the morphological alteration of the polymerization of pure actin.

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General description

Latrunculin A, a toxin extracted from the red sea sponge Latrunculia magnifica. It participates in vitro in the morphological alteration of the polymerization of pure actin. It forms a complex by binding with the nucleotide cleft of actin for actin filaments elongation.

Application

Latrunculin A has been used as medium supplementation for A549 cells to determine the internalization mechanism of CAV9 in A549 human lung carcinoma cells.

Biochem/physiol Actions

Latrunculin A inhibits actin polymerization by a different mechanism than cytochalasins. Latrunculin A disrupts microfilament-mediated processes.

UPC:
10161632
Condition:
New
HazmatClass:
No
MPN:
L5163-100UG
CAS:
76343-93-6
Temperature Control Device:
Yes

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