Biochem/physiol Actions FSL-1 (Pam2CGDPKHPKSF) is a synthetic lipoprotein that acts as a Toll-like Receptor 2/6 (TLR2/6) agonist and activator of nuclear transcription factor NF- K B. FSL-1 is based on the N-terminal part of the 44-kDa lipoprotein
Biochem/physiol Actions FSL-1 (Pam2CGDPKHPKSF) is a synthetic lipoprotein that acts as a Toll-like Receptor 2/6 (TLR2/6) agonist and activator of nuclear transcription factor NF- K B. FSL-1 is based on the N-terminal part of the 44-kDa lipoprotein
Biochem/physiol Actions SPP86 is a potent cell permeable inihbitor of RET tyrosine kinase with an IC 50 value of 8 nM and with some inhibitory activity at EphA1, FGFR1, Flt4, Lck and Yes. SPP86 does not inhibit p38, CSK, KIT, PDGF, Src or
Biochem/physiol Actions SPP86 is a potent cell permeable inihbitor of RET tyrosine kinase with an IC 50 value of 8 nM and with some inhibitory activity at EphA1, FGFR1, Flt4, Lck and Yes. SPP86 does not inhibit p38, CSK, KIT, PDGF, Src or
Biochem/physiol Actions SPP86 is a potent cell permeable inihbitor of RET tyrosine kinase with an IC 50 value of 8 nM and with some inhibitory activity at EphA1, FGFR1, Flt4, Lck and Yes. SPP86 does not inhibit p38, CSK, KIT, PDGF, Src or
Biochem/physiol Actions SPP86 is a potent cell permeable inihbitor of RET tyrosine kinase with an IC 50 value of 8 nM and with some inhibitory activity at EphA1, FGFR1, Flt4, Lck and Yes. SPP86 does not inhibit p38, CSK, KIT, PDGF, Src or
Biochem/physiol Actions INT131 is a brain penetrant, non-thiazolidinedione, highly potent and selective peroxisome proliferator-activated receptor gamma (PPARγ:) modulator (SPPARM) that displays anti-diabetic activities. INT131 is a partial,
Biochem/physiol Actions INT131 is a brain penetrant, non-thiazolidinedione, highly potent and selective peroxisome proliferator-activated receptor gamma (PPARγ:) modulator (SPPARM) that displays anti-diabetic activities. INT131 is a partial,
Biochem/physiol Actions INT131 is a brain penetrant, non-thiazolidinedione, highly potent and selective peroxisome proliferator-activated receptor gamma (PPARγ:) modulator (SPPARM) that displays anti-diabetic activities. INT131 is a partial,
Biochem/physiol Actions INT131 is a brain penetrant, non-thiazolidinedione, highly potent and selective peroxisome proliferator-activated receptor gamma (PPARγ:) modulator (SPPARM) that displays anti-diabetic activities. INT131 is a partial,
Biochem/physiol Actions AT1 is a cell penetrant Proteolysis Targeting Chimera (PROTAC) that selectively targets BET4 proteins for degradation by recruitments of ubiquitin E3 ligase. AT1 comprise (+)-JQ1 as a BET4 binding domain and E3 ligase
Biochem/physiol Actions AT1 is a cell penetrant Proteolysis Targeting Chimera (PROTAC) that selectively targets BET4 proteins for degradation by recruitments of ubiquitin E3 ligase. AT1 comprise (+)-JQ1 as a BET4 binding domain and E3 ligase