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PZ0106-25MGApplication SC-236 has been used as a COX-2 inhibitor to study its effects on the mechano-reflex in rats. Biochem/physiol Actions SC-236 exhibits anti-tumor activity in gastric cancer cells by modulating activator protein-1 (AP-1) expression -
PZ0106-5MGApplication SC-236 has been used as a COX-2 inhibitor to study its effects on the mechano-reflex in rats. Biochem/physiol Actions SC-236 exhibits anti-tumor activity in gastric cancer cells by modulating activator protein-1 (AP-1) expression -
R9782-25MGApplication RS-1 has been shown to enhance CRISPR genome editing efficiency. To see other small molecule CRISPR enhancers, visit sigma. -
R9782-5MGApplication RS-1 has been shown to enhance CRISPR genome editing efficiency. To see other small molecule CRISPR enhancers, visit sigma. -
SML0743-10MGApplication EUK-134 has been used as an antioxidant. EUK-134 has been used to determine the mechanism underlying hypoxia-inducible factor-1α: (HIF-1α:) stabilization in human aortic endothelial cells (HAECs). -
SML0743-50MGApplication EUK-134 has been used as an antioxidant. EUK-134 has been used to determine the mechanism underlying hypoxia-inducible factor-1α: (HIF-1α:) stabilization in human aortic endothelial cells (HAECs). -
SML1308-25MGBiochem/physiol Actions KT195 is a potent (IC 50 = 10 nM) and selective inhibitor of α:/β:-hydrolase domain-containing 6 (ABHD6), a serine hydrolase that acts as an alternative hydrolase of the endocannabinoid 2-arachidonoylglycerol -
SML1308-5MGBiochem/physiol Actions KT195 is a potent (IC 50 = 10 nM) and selective inhibitor of α:/β:-hydrolase domain-containing 6 (ABHD6), a serine hydrolase that acts as an alternative hydrolase of the endocannabinoid 2-arachidonoylglycerol -
SML2117-25MGBiochem/physiol Actions TCS-1102 (DORA-1) is a high-affinity (Ki = 3 nM against [3H]-TCS-1102 for binding hOX 1 R and Ki = 0.2 nM against [3H]-pyrrolylphenyl analog for binding hOX 2 R) dual orexin receptor antagonist (DORA) that potently inhibits -
SML2117-5MGBiochem/physiol Actions TCS-1102 (DORA-1) is a high-affinity (Ki = 3 nM against [3H]-TCS-1102 for binding hOX 1 R and Ki = 0.2 nM against [3H]-pyrrolylphenyl analog for binding hOX 2 R) dual orexin receptor antagonist (DORA) that potently inhibits -
SML2437-25MGBiochem/physiol Actions H-151 is an irreversible antagonist of the stimulator of interferon genes (STING) protein, a central signalling component of the cytosolic DNA sensing pathway. Although STING is a vital component of the innate immune -
SML2437-5MGBiochem/physiol Actions H-151 is an irreversible antagonist of the stimulator of interferon genes (STING) protein, a central signalling component of the cytosolic DNA sensing pathway. Although STING is a vital component of the innate immune
