SW-100, a selective histone deacetylase 6 (HDAC6) inhibitor with an IC 50 of 2.3 nM, shows at least 1000-fold selectivity for HDAC6 relative to all other HDAC isozymes. SW-100 displays a significantly improved ability to cross the
SW-100, a selective histone deacetylase 6 (HDAC6) inhibitor with an IC 50 of 2.3 nM, shows at least 1000-fold selectivity for HDAC6 relative to all other HDAC isozymes. SW-100 displays a significantly improved ability to cross the
InformationSW-044248 is a non-canonicalTop1inhibitor with a pattern of selective toxicity for NSCLC cells.TargetsTopo1In vitroSW044248 is selectively toxic for some NSCLC cell lines. SW044248 rapidly inhibits transcription, translation and DNA
InformationSW-044248 is a non-canonicalTop1inhibitor with a pattern of selective toxicity for NSCLC cells.TargetsTopo1In vitroSW044248 is selectively toxic for some NSCLC cell lines. SW044248 rapidly inhibits transcription, translation and DNA
InformationSW-044248 is a non-canonicalTop1inhibitor with a pattern of selective toxicity for NSCLC cells.TargetsTopo1In vitroSW044248 is selectively toxic for some NSCLC cell lines. SW044248 rapidly inhibits transcription, translation and DNA
InformationSW-044248 is a non-canonicalTop1inhibitor with a pattern of selective toxicity for NSCLC cells.TargetsTopo1In vitroSW044248 is selectively toxic for some NSCLC cell lines. SW044248 rapidly inhibits transcription, translation and DNA
InformationSW-044248 is a non-canonicalTop1inhibitor with a pattern of selective toxicity for NSCLC cells.TargetsTopo1In vitroSW044248 is selectively toxic for some NSCLC cell lines. SW044248 rapidly inhibits transcription, translation and DNA
InformationSW-044248 is a non-canonicalTop1inhibitor with a pattern of selective toxicity for NSCLC cells.TargetsTopo1In vitroSW044248 is selectively toxic for some NSCLC cell lines. SW044248 rapidly inhibits transcription, translation and DNA
InformationSW-044248 is a non-canonicalTop1inhibitor with a pattern of selective toxicity for NSCLC cells.TargetsTopo1In vitroSW044248 is selectively toxic for some NSCLC cell lines. SW044248 rapidly inhibits transcription, translation and DNA
InformationSW-044248 is a non-canonicalTop1inhibitor with a pattern of selective toxicity for NSCLC cells.TargetsTopo1In vitroSW044248 is selectively toxic for some NSCLC cell lines. SW044248 rapidly inhibits transcription, translation and DNA
InformationSW-044248 is a non-canonicalTop1inhibitor with a pattern of selective toxicity for NSCLC cells.TargetsTopo1In vitroSW044248 is selectively toxic for some NSCLC cell lines. SW044248 rapidly inhibits transcription, translation and DNA
InformationSW-044248 is a non-canonicalTop1inhibitor with a pattern of selective toxicity for NSCLC cells.TargetsTopo1In vitroSW044248 is selectively toxic for some NSCLC cell lines. SW044248 rapidly inhibits transcription, translation and DNA
InformationSB590885 is a potentB-Rafinhibitor withKiof 0.16 nM in a cell-free assay, 11-fold greater selectivity for B-Raf over c-Raf, no inhibition to other human kinases.In vitroSB590885 displays significant selectivity for B-Raf over c-Raf with
InformationSB590885 is a potentB-Rafinhibitor withKiof 0.16 nM in a cell-free assay, 11-fold greater selectivity for B-Raf over c-Raf, no inhibition to other human kinases.In vitroSB590885 displays significant selectivity for B-Raf over c-Raf with
SB590885 is a potent B-Raf inhibitor with Ki of 0.16 nM, 11-fold greater selectivity for B-Raf over c-Raf, no inhibition to other human kinases.A potent Raf-B inhibitor.
SB590885 is a potent B-Raf inhibitor with Ki of 0.16 nM, 11-fold greater selectivity for B-Raf over c-Raf, no inhibition to other human kinases.A potent Raf-B inhibitor.
SB590885 is a potent B-Raf inhibitor with Ki of 0.16 nM, 11-fold greater selectivity for B-Raf over c-Raf, no inhibition to other human kinases.A potent Raf-B inhibitor.
SB590885 is a potent B-Raf inhibitor with Ki of 0.16 nM, 11-fold greater selectivity for B-Raf over c-Raf, no inhibition to other human kinases.A potent Raf-B inhibitor.
SB590885 is a potent B-Raf inhibitor with Ki of 0.16 nM, 11-fold greater selectivity for B-Raf over c-Raf, no inhibition to other human kinases.A potent Raf-B inhibitor.
SB590885 is a potent B-Raf inhibitor with Ki of 0.16 nM, 11-fold greater selectivity for B-Raf over c-Raf, no inhibition to other human kinases.A potent Raf-B inhibitor.
SB590885 is a potent B-Raf inhibitor with Ki of 0.16 nM, 11-fold greater selectivity for B-Raf over c-Raf, no inhibition to other human kinases.A potent Raf-B inhibitor.
SB590885 is a potent B-Raf inhibitor with Ki of 0.16 nM, 11-fold greater selectivity for B-Raf over c-Raf, no inhibition to other human kinases.A potent Raf-B inhibitor.