Quisinostat (JNJ-26481585) 2HCl is a novel second-generationHDACinhibitor with highest potency for HDAC1 withIC50of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8,...
Quisinostat (JNJ-26481585) 2HCl is a novel second-generationHDACinhibitor with highest potency for HDAC1 withIC50of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8,...
Ac-VEID-AFC is a fluorogenic substrate for caspase-6 (K|m|=30μM; K|cat|/K|m|=168000 M|-1|sec|-1|) and related cysteine proteases. The sequence is based on the lamin A site of cleavage.
Ac-VEID-AFC is a fluorogenic substrate for caspase-6 (K|m|=30μM; K|cat|/K|m|=168000 M|-1|sec|-1|) and related cysteine proteases. The sequence is based on the lamin A site of cleavage.
Ethidium Homodimer-III (EthD-III) is an alternative to Ethidium Homodimer-I (EthD-I). It exhibits a fluorescence spectrum similar to that of EthD-I; however, upon binding to DNA, EthD-III produces significantly brighter fluorescence than EthD-I.
Ethidium Homodimer-III (EthD-III) is an alternative to Ethidium Homodimer-I (EthD-I). It exhibits a fluorescence spectrum similar to that of EthD-I; however, upon binding to DNA, EthD-III produces significantly brighter fluorescence than EthD-I.
Ethidium Homodimer-III (EthD-III) is an alternative to Ethidium Homodimer-I (EthD-I). It exhibits a fluorescence spectrum similar to that of EthD-I; however, upon binding to DNA, EthD-III produces significantly brighter fluorescence than EthD-I.
Ethidium Homodimer-III (EthD-III) is an alternative to Ethidium Homodimer-I (EthD-I). It exhibits a fluorescence spectrum similar to that of EthD-I; however, upon binding to DNA, EthD-III produces significantly brighter fluorescence than EthD-I.