L-LYSINE MONOHYDROCHLORIDE BIOULTRA >= 99.5 % AT (C005B-055672)

General description

L-Lysine is an essential amino acid, not generated by the body, instead must be supplemented through food.

Application

L-Lysine monohydrochloride has been used:

• to study its effect on mRNA decay and destruction using mammalian cells
• to determine its effec on aTC1-6 cell proliferation
• to study the dynamics of the phosphoproteome upon amino acid supplement removal in the growth medium

Biochem/physiol Actions

L-Lysine is associated with a number of biochemical reactions such as acetylation, O-linked glycosylation, ubiquitination and protein methylation. Lysine participates in the regulation of NO (nitric oxide) synthesis. It possesses antiviral activity, therefore it is used in the treatment of Herpes simplex. L-Lysine is believed to prevent osteoporosis of bones, which is a characteristic of vascular calcification. Glutaric aciduria type I and pyridoxine-dependent epilepsy occurs due to lack of L-lysine catabolic pathway. Hydroxylysine is a component of collagen

Molecular Weight: 182.65. Empirical Formula: C₆H₁₄N₂O₂ · HCl. linearFormula: H₂N(CH₂)₄CH(NH₂)CO₂H·HCl. product line: BioUltra. Quality Level: 200. Assay: ≥. 99.5% (AT). form: powder or crystals. optical activity: [α. ]20/D +20.5±0.5°, c :  . 5% in 5 M HCl. technique(s): cell culture | mammalian: suitable. impurities: insoluble matter, passes filter test, ≤. 0.3% foreign amino acids. ign. residue: ≤. 0.1% (as SO₄). loss: ≤. 0.5% loss on drying, 20 °C (HV). color: white. pH: 5.0-6.0 (25 . °C, 0.5 . M in H₂O). mp: 263 . °C (dec.) (lit.). solubility: H₂O: 0.5 . M at . 20 . °C, clear, colorless. anion traces: sulfate (SO₄^2-): ≤. 100 . mg/kg. cation traces: Al: ≤. 5 . mg/kg, As: ≤. 0.1 . mg/kg, Ba: ≤. 5 . mg/kg, Bi: ≤. 5 . mg/kg, Ca: ≤. 10 . mg/kg, Cd: ≤. 5 . mg/kg, Co: ≤. 5 . mg/kg, Cr: ≤. 5 . mg/kg, Cu: ≤. 5 . mg/kg, Fe: ≤. 5 . mg/kg, K: ≤. 50 . mg/kg, Li: ≤. 5 . mg/kg, Mg: ≤. 5 . mg/kg, Mn: ≤. 5 . mg/kg, Mo: ≤. 5 . mg/kg, NH₄⁺: ≤. 100 . mg/kg, Na: ≤. 50 . mg/kg, Ni: ≤. 5 . mg/kg, Pb: ≤. 5 . mg/kg, Sr: ≤. 5 . mg/kg, Zn: ≤. 5 . mg/kg. λ: 0.5 . M in H₂O. UV absorption: λ. : 260 . nm A_max: 0.1, λ. : 280 . nm A_max: 0.1. SMILES string: OC([C@@H](N)CCCCN): O.[H]Cl. InChI: 1S/C6H14N2O2.ClH/c7-4-2-1-3-5(8)6(9)10. /h5H,1-4,7-8H2,(H,9,10). 1H/t5-. /m0./s1. InChI key: BVHLGVCQOALMSV-JEDNCBNOSA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 2. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).