L-HISTIDINOL DIHYDROCHLORIDE (C005B-020533)

Application

L-Histidinol dihydrochloride has been used:

• as a reagent in urinary metabolite analysis
• for making DT40 knockout cells, where cells were selected in 1mg/ml histidinol
• for inducing amino acid deprivation in HepG2 cells

Biochem/physiol Actions

Precursor of histamine; reversible inhibitor of protein synthesis.

Molecular Weight: 214.09. Empirical Formula: C₆H₁₁N₃O · 2HCl. Quality Level: 200. Assay: ≥. 98% (TLC). form: powder. color: white to off-white. mp: 198-201 . °C (dec.) (lit.). application(s): cell analysis. SMILES string: Cl[H].Cl[H].N[C@H](CO)Cc1c[nH]cn1. InChI: 1S/C6H11N3O.2ClH/c7-5(3-10)1-6-2-8-4-9-6. . /h2,4-5,10H,1,3,7H2,(H,8,9). 2*1H/t5-. . /m0../s1. InChI key: FRCAFNBBXRWXQA-XRIGFGBMSA-N. Gene Information: human ... HRH1(3269)
mouse ... HRH1(15465)
rat ... HRH1(24448). Pictograms: GHS07. Signal Word: Warning. Hazard Statements: H315 - H319 - H335. Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338. Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3. Target Organs: Respiratory system. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves.