L-CYSTINE MEETS EP TESTING SPECIFICATIONS BIOXTRA 98.5-101.0% FROM NON-ANIMAL SOURCE CELL CULTURE TESTED (C005B-049406)

Application

L-Cystine has been used as a supplement in astroglial-conditioned media to culture cerebral astroglia. It has been used in several techniques, such as HPLC-FD, UHPLC-UV, UHPLC-MS, and triple quadrupole tandem mass spectrometry (UHPLC-MS/MS), to differentiate BMAA (β-N-methylamino-L-alanine), the cyanobacterial neurotoxin, from other diamino acids.
L-Cystine has been used as a supplement in oocyte culture media to improve oocyte maturation and parthenogenesis of embryonic development.

Biochem/physiol Actions

Cystinuria is characterized with renal transport and excretion of L-Cystine. Cysteine is one of the functional amino acids that are associated with growth, reproduction, maintenance and immunity. Cysteine is a source of disulfide linkage in protein and is associated with sulfur transport. At physiological pH, cysteine undergoes rapid oxidation to form cystine. Reduced availability of cysteine or cystine, influences leukocyte metabolism. L-Cystine is necessary for oxygen production and LDL (low density lipoprotein) modification by arterial smooth muscle cells.

Molecular Weight: 240.30. Empirical Formula: C₆H₁₂N₂O₄S₂. linearFormula: [-SCH₂CH(NH₂)CO₂H]₂. biological source: non-animal source. Quality Level: 200. Agency: meets EP testing specifications. product line: BioXtra. Assay: 98.5-101.0%. form: powder. technique(s): cell culture | mammalian: suitable. impurities: endotoxin, tested. color: white to off-white. mp: >. 240 . °C (dec.) (lit.). solubility: 1 M HCl: 100 . mg/mL. web metadata keyword.default: L-amino acid, active isomer, non-essential amino acid. application(s): peptide synthesis. SMILES string: N[C@@H](CSSC[C@H](N)C(O): O)C(O): O. InChI: 1S/C6H12N2O4S2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1. InChI key: LEVWYRKDKASIDU-IMJSIDKUSA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).