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l-655,708 (c15-1892-610)

L-655 708 (C005B-455721)

Catalog No.
C005B-455721
Manufacturer No.
L9787-5MG
Manufacturer Name
Sigma-Aldrich
Quantity
5
Unit of Measure
MG

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Application L-655,708 has been used as an α:5 GABAA receptor inverse agonist to inhibit the discriminative stimulus of propofol in a dose-dependent manner. Biochem/physiol Actions L-655,708 is an inverse agonist of the α:5

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Application

L-655,708 has been used as an α5 GABAA receptor inverse agonist to inhibit the discriminative stimulus of propofol in a dose-dependent manner.

Biochem/physiol Actions

L-655,708 is an inverse agonist of the α5 γ-Aminobutyric acid type A (GABAA) receptor. It has an ability to increase cognition in rats.

Novel ligand selective for the benzodiazepine site of GABAA receptors which contain the α5 subunit.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

UPC:
42161621
Condition:
New
HazmatClass:
No
MPN:
L9787-5MG
CAS:
130477-52-0

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