KZR-504 (C007B-363595)

Catalog No.: C007B-363595
Manufacturer No.: K650744-100mg
Manufacturer Name: Aladdin Scientific
Quantity: 1
Unit of Measure: EA

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Description
Specifications

KZR-504 is a highly selective inhibitor of immunoproteasome low molecular mass polypeptide 2 (LMP2) , with IC 50 s of 51 nM, 4.274 μM for LMP2 and LMP7, respectively. KZR-504 is of interest for the treatment of autoimmune diseaseIn VivoEvaluating the inhibition of LMP2, and antitargets LMP7 and β5, in mouse tissues reveals that KZR-504 (compound 12) is both selective and potent in vivo with >50% target inhibition achieved at >1 mg/kg in all tissues tested except brain . MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:IC50: 51 nM (LMP2), 4.274 μM (LMP7).

Specifications and Purity: ≥98%

Molecular Formula: C21H23N3O6

Molecular Weight: 413.42

UPC:: 41101902
Condition:: New
HazmatClass:: No
WeightUOM:: LB
MPN:: K650744-100mg
CAS:: 1629052-78-3
Product Size:: 100mg

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