KOLLIPHOR EL PH-RANGE 6.0 - 8.0 (C005B-053120)

General description

Kolliphor^® EL is a nonionic solubilizer and emulsifier made by reacting castor oil with ethylene oxide. It is a pale yellow oily liquid that is clear at temperatures above 26°C. It has a faint but characteristic odour.

Kolliphor^® EL is polyethylene oxide surfactant and is viscous in nature. It has a hydrophobic-lipophilic balance value in the range of 12-14.

Application

Kolliphor^® EL has been used as a detergent to improve the solubility of dye and to increase the transmembrane permeation. It has been used as a vehicle for drug/stimulant delivery in cells.

Used to emulsify and solubilize oils and other water-insoluble substances. Cremophor is the brand name for a range of non-ionic polyethoxylated detergents. It was originally developed for use as solubilizers and emulsifiers.
This research grade product is intended for use in R&D and development only.

Biochem/physiol Actions

Kolliphor^® EL is used in lipid-based formulations for drugs and solubilization of cosmetics. Kolliphor EL is suitable for the production of semi-solid and liquid formulations of water-insoluble actives and other hydrophobic compounds. Due to its emulsification functionality, it finds application in biological membrane- based drug transport studies.

Other Notes

A derivative of castor oil and ethylene oxide.

Legal Information

Cremophor is a registered trademark of BASF SE

Kolliphor is a registered trademark of BASF

description: non-ionic. Quality Level: 200. form: liquid. mol wt: ~2500 . g/mol. pH range: 6.0-8.0. HLB: 12 - 14. application(s): sample preservation. InChI: 1S/C4H7Cl2NO2/c5-1-3(2-6)9-4(7)8/h3H,1-2H2,(H2,7,8). InChI key: JMNCUXPHXKHBPY-UHFFFAOYSA-N. Storage Class Code: 10 - Combustible liquids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves.