KN-62 (C005B-013388)

Biochem/physiol Actions

Selectively inhibits rat brain Ca²⁺/calmodulin-dependent protein kinase II.

Features and Benefits

This compound is featured on the Ca/CaMKs and P2 Receptors: P2X Ion Channel Family pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Molecular Weight: 721.84. Empirical Formula: C₃₈H₃₅N₅O₆S₂. biological source: synthetic (organic). Quality Level: 200. Assay: ≥. 95%. form: powder. color: yellow. mp: 130 . °C. solubility: 45% (w/v) aq 2-hydroxypropyl-β. -cyclodextrin: 0.93 . mg/mL, methanol: 10 . mg/mL, DMSO: 12 . mg/mL, chloroform: 20 . mg/mL. storage temp.: −. 20°C. SMILES string: O: S(OC1: CC: C(C[C@@H](C(N2CCN(C3: CC: CC: C3)CC2): O)N(C)S(C4: CC: CC5: C4C: CN: C5)(: O): O)C: C1)(C6: CC: CC7: C6C: CN: C7): O. InChI: 1S/C38H35N5O6S2/c1-41(50(45,46)36-11-5-7-29-26-39-19-17-33(29)36)35(38(44)43-23-21-42(22-24-43)31-9-3-2-4-10-31)25-28-13-15-32(16-14-28)49-51(47,48)37-12-6-8-30-27-40-20-18-34(30)37/h2-20,26-27,35H,21-25H2,1H3/t35-/m0/s1. InChI key: RJVLFQBBRSMWHX-DHUJRADRSA-N. Gene Information: human ... P2RX7(5027). Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).