KITALYSIS(TM) HIGH-THROUGHPUT MEDIUM (5 6 7) RING CLOSING METATHESIS REACTION SCREENING KIT - PACK OF 2

Application

Screening kit for ring closing metathesis. Step-by-step user guides and a downloadable experimental excel sheets are provided in the below hyperlinks.

Step-by-Step Guide for Ring Closing Metathesis/Cross Metathesis Reaction Screening Kit

Downloadable experimental excel file

Each kit contains 2 customizable screening sets that include the following components:

• 6x4 pre-weighed catalysts in glass microvials loaded with stir bars and topped with cap mat.
• 2 (2 mL) ampules each of of ClPh, PhMe, i-PrOAc, Me-THF, and TFA.
• 1 KitAlysis 24-well reaction block replacement film.
• 4 empty substrate stock solution reaction vials with stir bars.
• 1 internal standard.

Monitor reaction progress via TLC-MS by following this protocol

Best when used with KitAlysis Benchtop Inertion Box and 24-well Reaction Block (sold separately).

Features and Benefits

• Designed and tested by synthetic chemists.
• Easily run 24-microscale reaction in parallel.
• 20 μmol reactions with 1 μmol catalyst (5 mol%), 0.2 M concentration, and optional TFA additive.
• Customizable and downloadable excel template for quick calculations and easy incorporation into electronic laboratory notebooks.

Legal Information

KitAlysis is a trademark of Sigma-Aldrich Co. LLC

reaction suitability: core: palladium, reaction type: Buchwald-Hartwig Cross Coupling Reaction, reaction type: Heck Reaction, reaction type: Hiyama Coupling, reaction type: Negishi Coupling, reaction type: Sonogashira Coupling, reaction type: Stille Coupling, reaction type: Suzuki-Miyaura Coupling. storage temp.: 2-8°C. Pictograms: GHS02,GHS05,GHS07,GHS08,GHS09. Signal Word: Danger. Hazard Statements: H228 - H302 + H332 - H315 - H318 - H336 - H361d - H373 - H411. Precautionary Statements: P210 - P273 - P280 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313. Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Flam. Sol. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 2 - STOT SE 3. Target Organs: Central nervous system. Supp Hazards: EUH019. Storage Class Code: 4.1B - Flammable solid hazardous materials. WGK: WGK 3.