KH-CB20, an E/Z mixture, is a potent and selective inhibitor of CLK1 and the closely related isoform CLK4 , with an IC 50 of 16.5 nM for CLK1 . KH-CB20 can also inhibit DYRK1A ( IC 50 =57.8 nM) and CLK3 ( IC 50 =488 nM)In VitroKH-CB20 shows selectivity for CLK1 (IC 50 =16.5 nM) over DYRK1A (IC 50 =57.8 nM) and CLK3 (IC 50 =488 nM). MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:CLK1 16.5 nM (IC 50 ) DYRK1A 57.8 nM (IC 50 ) CLK3 488 nM (IC 50 ).
Specifications and Purity: ≥99%
Molecular Formula: C15H13Cl2N3O2
Molecular Weight: 338.19
- UPC:
- 41103816
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- K648788-5mg
- CAS:
- 1354448-60-4
- Product Size:
- 5mg
akash.verma@cenmed.com
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