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kb-r7943 (c15-1220-513)

KB-R7943 (C005B-022747)

Catalog No.
C005B-022747
Manufacturer No.
K4144-25MG
Manufacturer Name
Sigma-Aldrich
Quantity
25
Unit of Measure
MG

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Biochem/physiol Actions KB-R7943 inhibits the reversed Na(+)/Ca(2+) exchanger, NCX. In cardiomyocytes, Ca2+ is released from intracellular stores during contraction, and sequestered again during relaxation.

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Biochem/physiol Actions

KB-R7943 inhibits the reversed Na(+)/Ca(2+) exchanger, NCX. In cardiomyocytes, Ca2+ is released from intracellular stores during contraction, and sequestered again during relaxation. NCX is the primary mechanism that prevents Ca2+ overload due to influx of calcium across the plasma membrane.

Molecular Weight: 427.50. Empirical Formula: C16H17N3O3S·CH3SO3H. Quality Level: 100. Assay: ≥. 98% (HPLC). form: powder. color: off-white to tan. solubility: DMSO: >. 10 . mg/mL. storage temp.: 2-8°C. SMILES string: CS(O)(: O): O.NC(: N)SCCc1ccc(OCc2ccc(cc2)[N+]([O-]): O)cc1. InChI: 1S/C16H17N3O3S.CH4O3S/c17-16(18)23-10-9-12-3-7-15(8-4-12)22-11-13-1-5-14(6-2-13)19(20)21. 1-5(2,3)4/h1-8H,9-11H2,(H3,17,18). 1H3,(H,2,3,4). InChI key: WGIKEBHIKKWJLG-UHFFFAOYSA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.
UPC:
12142003
Condition:
New
HazmatClass:
No
MPN:
K4144-25MG
CAS:
182004-64-4

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