IWR-1-endo

Catalog No.: C007B-196328
Manufacturer No.: I408301-1ml
Manufacturer Name: Aladdin Scientific
Quantity: 1
Unit of Measure: EA

Enjoy exclusive benefits including discounted pricing on orders by contacting our Sales Executives to open an account. Contact Us

Description
Specifications

InformationIWR-1-endo IWR-1-endo (endo-IWR 1) is a Wnt pathway inhibitor with IC50 of 180 nM in L-cells expressing Wnt3A, induces Axin2 protein levels and promotes β-catenin phosphorylation by stabilizing Axin-scaffolded destruction complexes.In vitroAlthough both IWR-1 and XAV939 act as reversible Wnt pathway inhibitors and exhibit similar pharmacological effects both in vitro and in vivo, IWR-1 exerts its effect via interaction with Axin, while XAV939 binds TNKS directly.In vivoCell Datacell lines：HCT116, A2780, and U2OS cellsConcentrations：Incubation Time：Powder Purity:≥98%.

Specifications and Purity: 10mM in DMSO

Molecular Formula: C25H19N3O3

Molecular Weight: 409.44

UPC:: 42294919
Condition:: New
HazmatClass:: No
WeightUOM:: LB
MPN:: I408301-1ml
CAS:: 1127442-82-3
Product Size:: 1ml

Cenmed Satisfaction Guarantee

At Cenmed, your confidence and satisfaction are paramount. We guarantee the quality and reliability of our extensive range of clinical and laboratory supplies. If you're not completely satisfied with your purchase, we offer a straightforward return process and dedicated support to resolve your concerns promptly. Our commitment ensures that you can order with confidence, knowing that Cenmed is dedicated to superior service and customer satisfaction. Trust us to meet your needs with every order, backed by our promise of excellence. Learn more in Help & FAQs.

"Cenmed provides me access to the same products/services normally reserved for much larger labs than mine. I was presently surprised by their product offering."