IWP-3 is an potent inhibitor of Wnt production with an IC 50 of 40 nM. IWP-3 inhibits Porcupine (Porcn) function thereby blocking palmitoylation of Wnt proteins. IWP-3 inhibits CK1γ3 and CK1ε only moderately and does not inhibit CK1α.Form:Solid.
Specifications and Purity: ≥98%
Molecular Formula: C22H17FN4O2S3
Molecular Weight: 484.59
PubChem CID: 2155389
Isomeric SMILES: CC1=CC2=C(C=C1)N=C(S2)NC(=O)CSC3=NC4=C(C(=O)N3C5=CC=C(C=C5)F)SCC4
- UPC:
- 41101808
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- I647349-5mg
- CAS:
- 687561-60-0
- Product Size:
- 5mg
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