Irinotecan is a topoisomerase I inhibitor for LoVo cells and HT-29 cells with IC50 of 15.8 μM and 5.17 μM, respectively.Irinotecan hydrochloride has been used:in combination with 5-fluorouracil for screening growth inhibitory functionality in MDA-MB-231 breast cancer cells.in chemosensitivity screening of high-grade appendiceal (HGA) and low-grade appendiceal (LGA) organoids.as a chemotherapeutic agent in the cytotoxicity studies in combination with heat shock proteins inhibitors (HPSC1) in HT29 colon cancer cells.
Specifications and Purity: ≥99%
Molecular Formula: C33H38N4O6
Molecular Weight: 586.68
PubChem CID: 60838
Isomeric SMILES: CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)O)C2=NC5=C1C=C(C=C5)OC(=O)N6CCC(CC6)N7CCCCC7
Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/I127961-SCI_f6284aa4bbba755679650082818ba42e.pdf
- UPC:
- 10161818
- Condition:
- New
- HazmatClass:
- Yes
- WeightUOM:
- LB
- MPN:
- I127961-500mg
- CAS:
- 97682-44-5
- Health Hazards:
- Corrosive
- Product Size:
- 500mg
- Hazard Statement Codes:
- H373:H361:H318:H315:H302
- Precautionary Statement Codes:
- P501:P405:P362+P364:P332+P313:P308+P313:P305+P351+P338:P302+P352:P301+P312:P330:P321:P314:P310:P280:P270:P264:P260:P202:P201
akash.verma@cenmed.com
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