IPRATROPIUM BROMIDE MONOHYDRATE (C005B-056096)

Application

Ipratropium bromide monohydrate has been used for the inhibition of peripheral muscarinic receptors in rats.

Biochem/physiol Actions

Ipratropium bromide monohydrate is a nonselective muscarinic acetylcholine receptor antagonist and a bronchodilator. In nebulized form, it is used for treating asthma and obstructive pulmonary diseases. It acts as a β₂ adrenoreceptor agonist. Ipratropium bromide monohydrate is an anticholinergic agent and competes with acetylcholine. It promotes bronchodilation by stimulating sympathetic pathways.

Features and Benefits

This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Other Notes

N-isopropyl quaternary salt of atropine.

Molecular Weight: 430.38. Empirical Formula: C₂₀H₃₀BrNO₃ · H₂O. Quality Level: 200. Assay: ≥. 98% (TLC). form: powder. color: white. solubility: H₂O: 10 . mg/mL. originator: Boehringer Ingelheim. SMILES string: O.[Br-].CC(C)[N@+]1(C)[C@H]2CC[C@@H]1C[C@@H](C2)OC(: O)C(CO)c3ccccc3. InChI: 1S/C20H30NO3.BrH.H2O/c1-14(2)21(3)16-9-10-17(21)12-18(11-16)24-20(23)19(13-22)15-7-5-4-6-8-15. . /h4-8,14,16-19,22H,9-13H2,1-3H3. 1H. 1H2/q+1. . /p-1/t16-,17+,18+,19?,21?. . . InChI key: KEWHKYJURDBRMN-XSAPEOHZSA-M. Gene Information: human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133). Pictograms: GHS07. Signal Word: Warning. Hazard Statements: H302 + H332 - H319. Precautionary Statements: P261 - P264 - P271 - P301 + P312 - P304 + P340 + P312 - P305 + P351 + P338. Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2. Storage Class Code: 11 - Combustible Solids. WGK: WGK 2.