Biochem/physiol Actions
Interleukin 18, also known as interferon-γ-inducing factor (IGIF) and IL-1γ, is a proinflammatory cytokine. It is an inducer of IFN-γ and Th1 (T cell helper type 1) responses (cell differentiation, cell-mediated cytotoxicity and inflammation). IL-18 induces the migration of microvascular endothelial cells.
Physical form
Lyophilized from 20 mM Tris , 500 mM NaCl, 0.5 mM EDTA, 1 mM TCEP, 0.05% (w/v) PEG8000 pH 8.0 with 5% Trehalose,and 50 μg BSA per μg IL-18
Analysis Note
The biological activity is measured by its ability to induce mouse IFN-γ production by activated mouse T cells.
biological source: rat. Quality Level: 200. recombinant: expressed in E. coli. Assay: >. 97% (SDS-PAGE). form: lyophilized powder. potency: 10-60 . ng/mL ED50. mol wt: predicted mol wt ~18.4 . kDa. packaging: pkg of 25 . μ. g. impurities: endotoxin, tested. UniProt accession no.: Q16552. shipped in: dry ice. storage temp.: −. 20°C. Gene Information: rat ... Il18(29197). Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.- UPC:
- 51142106
- Condition:
- New
- HazmatClass:
- No
- MPN:
- I0531-25UG
- Temperature Control Device:
- Yes
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