INTERFERON BETA RECOMBINANT RAT

Biochem/physiol Actions

Interferon β belongs to the type 1 interferon family pf proteins. It is also needed for the inhibition of tumor cell growth via cell death, S-phase increase and mediating differentiation. It is also important for bone homeostasis.

Cytokine with anti-viral, anti-proliferative, immunoregulatory, and proinflammatory activities.

Physical form

Lyophilized from phosphate buffered saline (PBS) containing 125 mM trehalose.

Analysis Note

The biological activity is determined in the cytopathic effect inhibition assay using rat epithelial-like (RATEC) cells with vesicular stomatitis virus (VSV). The cytopathic effect of 50% is produced with approximately 1 unit/ml interferon. Since there is no international rat interferon β standard, units are determined with respect to the NIH international standard reference for mouse interferon α/β.

biological source: rat. Quality Level: 200. recombinant: expressed in CHO cells. Assay: ≥. 95%. form: lyophilized powder. mol wt: ~20 . kDa. packaging: pkg of 1 . vial. concentration: ≥. 100000 . units/mL. technique(s): cell culture | mammalian: suitable. UniProt accession no.: P70499. shipped in: dry ice. storage temp.: −. 70°C. Gene Information: rat ... Ifnb1(24481). Storage Class Code: 13 - Non Combustible Solids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).