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InsR and IGF-1R inhibitor. It inhibits cell proliferation and tumor growth in models of pancreatic ductal adenocarcinoma and breast cancer. (C003B-255213)

InsR and IGF-1R inhibitor. It inhibits cell proliferation and tumor growth in models of pancreatic ductal adenocarcinoma and breast cancer. (C003B-255213)

Catalog No.
C003B-255213
Manufacturer No.
B5072-5 mg
Manufacturer Name
LKT LABORATORIES
Quantity
1
Unit of Measure
EA

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BMS-754807 is an inhibitor of the insulin receptor (InsR) and IGF-1R that exhibits anticancer chemotherapeutic activity. BMS-754807 enhances the efficacy of other co-administered chemotherapeutics, decreasing levels of activated Akt, increasing

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BMS-754807 is an inhibitor of the insulin receptor (InsR) and IGF-1R that exhibits anticancer chemotherapeutic activity. BMS-754807 enhances the efficacy of other co-administered chemotherapeutics, decreasing levels of activated Akt, increasing cleavage of PARP and caspase 3, and inhibiting proliferation in pancreatic ductal adenocarcinoma cells and breast cancer cells in vitro and growth of tumor xenografts in vivo.
UPC:
51182302
HazmatClass:
No
WeightUOM:
LB
MPN:
B5072-5 mg
CAS:
1001350-96-4

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