Imlunestrant (LY-3484356) is an orally active, potent and selective estrogen receptor degrader (SERD) with pure antagonistic properties. Imlunestrant results in sustained inhibition of ER-dependent gene transcription and cell growth. Imlunestrant can be used for the research of ER-positive (ER+) advanced breast cancer (aBC) and endometrial endometrioid cancer (EEC).In VitroLY3484356 shows favorable pharmacokinetic (PK) properties, including antitumor activity in ESR1 mutants. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:Solid.
Molecular Formula: C29H24F4N2O3
Molecular Weight: 524.51
PubChem CID: 146603228
Isomeric SMILES: C1C(CN1CCOC2=CC=C(C=C2)[C@@H]3C4=C5C=CC(=CC5=NC=C4C6=C(O3)C=C(C=C6)C(F)(F)F)O)CF
- UPC:
- 41105341
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- I651517-5mg
- CAS:
- 2408840-26-4
- Product Size:
- 5mg
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