IMIQUIMOD UNITED STATES PHARMACOPEIA (USP) REFERENCE STANDARD (C005B-092389)

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Imiquimod USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Biochem/physiol Actions

Imiquimod is a caspase 3 activator, which directly induces procaspase 3 cleavage to active caspase 3. Imiquimod induces apoptosis in vivo in basal cell carcinoma. Its anti-tumor activity is related to the induction of apoptosis. Imiquimod has anti-angiogenic, anti-inflammatory, anti-viral activities. Imiquimod also acts as an immune response modulator inducing the secretion of various cytokines and chemokines.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  â€‹

Other Notes

USP issued SDS can be found here.

Sales restrictions may apply.

Molecular Weight: 240.30. Empirical Formula: C₁₄H₁₆N₄. grade: pharmaceutical primary standard. API family: imiquimod. manufacturer/tradename: USP. application(s): pharmaceutical (small molecule). format: neat. SMILES string: CC(C)Cn1cnc2c(N)nc3ccccc3c12. InChI: 1S/C14H16N4/c1-9(2)7-18-8-16-12-13(18)10-5-3-4-6-11(10)17-14(12)15/h3-6,8-9H,7H2,1-2H3,(H2,15,17). InChI key: DOUYETYNHWVLEO-UHFFFAOYSA-N. Gene Information: human ... TLR7(51284). Pictograms: GHS06. Signal Word: Danger. Hazard Statements: H301 - H315 - H319. Precautionary Statements: P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338 - P332 + P313. Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2. Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.