General description
IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activities primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowl disease and diseases affiliated with retroviruses HIV and HTLV-I.
Recombinant human IL-15 is a 12.9 kDa protein consisting of 115 amino acid residues.
Quality
The ED50 was determined by its ability to stimulate the proliferation of mouse CTLL-2 cells. The expected ED50 is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 10^6 units/mg.
Physical form
Product is presented in 10 mM Sodium Phosphate, pH 8.5 and is filtered through a 0.2 micron filter before lyophilization.
impurities: <. 0.1 . μ. g/mg protein endotoxin (<1 EU/μ. g). Quality Level: 100. UniProt accession no.: P40933. shipped in: dry ice. Storage Class Code: 11 - Combustible Solids. WGK: WGK 1.- UPC:
- 10101510
- Condition:
- New
- HazmatClass:
- No
- MPN:
- GF327
- Temperature Control Device:
- Yes
akash.verma@cenmed.com
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