HYDROGEN CHLORIDE 2.0M SOLUTION IN DIETHYL ETHER (C005B-078090)

General description

The product is a 2M solution of hydrogen chloride in diethyl ether.

Application

Hydrogen chloride solution can be used as a reagent to synthesize:

• Cyanohydrin alkyl ethers via chiral Bronsted acid-mediated hydrocyanation of vinyl ethers with silyl cyanides.
• N, N-Dimethylaniline hydrochloride salts via Pd-catalyzed Buchwald-Hartwig amination of aryl triflates with dimethylamines.

It can also be used as a catalyst for the amidation of carboxylic acids with amines to synthesize amides.

Molecular Weight: 36.46. Empirical Formula: HCl. form: liquid. Quality Level: 100. concentration: 1.90-2.20 . M (with NaOH, titration), 2.0 . M in diethyl ether. bp: 34.6 . °C. density: 0.747 . g/mL . at 25 . °C. storage temp.: 2-8°C. SMILES string: Cl. InChI: 1S/ClH/h1H. InChI key: VEXZGXHMUGYJMC-UHFFFAOYSA-N. Pictograms: GHS02,GHS05,GHS06. Signal Word: Danger. Hazard Statements: H224 - H290 - H302 - H331 - H336 - H412. Precautionary Statements: P210 - P233 - P273 - P301 + P312 - P304 + P340 + P311 - P403 + P233. Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Flam. Liq. 1 - Met. Corr. 1 - STOT SE 3. Target Organs: Respiratory system. Supp Hazards: EUH019 - EUH066. Storage Class Code: 3 - Flammable liquids. WGK: WGK 1. Flash Point(F): -29.2 °F - closed cup. Flash Point(C): -34 °C - closed cup.