HUP30 is a vasodilating agent. HUP30 stimulates soluble guanylyl cyclase, activate K + channels, and blocks extracellular Ca 2+ influx.In VitroHUP30 inhibits Phenylephrine-induced aorta contraction with an IC 50 value of 3.9 μM. HUP30 (100 μM) increases cGMP levels in Phenylephrine-stimulated aorta. HUP30 causes an antispasmodic effect on rat aorta rings contracted by 25/30 mM K + , with an IC 50 value of 7.5 μM. HUP30 (3-100 μM) inhibits both extracellular Ca 2+ influx and Ca 2+ mobilization induced by Phenylephrine. HUP30 (10-100 μM) inhibits the current in single tail artery myocytes. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:Solid.
Specifications and Purity: ≥99%
Molecular Formula: C14H15N3O3S
Molecular Weight: 305.35
PubChem CID: 739510
Isomeric SMILES: C1CCC(CC1)C(=O)NC2=NC3=C(S2)C=C(C=C3)[N+](=O)[O-]
- UPC:
- 41102412
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- H651067-5mg
- CAS:
- 312747-21-0
- Product Size:
- 5mg
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