Biochem/physiol Actions
(1R,3S)-HPA-12 is a ceramide (Cer) analog that acts as a Cer transporter (CERT) antagonist and selectively inhibits cellular Cer conversion to sphingomyelin (SM), but not to glucosylceramide, by blocking CERT-mediated Cer ER-to-Golgi transport. Common culture dosing range: 1-10 μM.
- UPC:
- 42202401
- Condition:
- New
- HazmatClass:
- No
- MPN:
- SML2894-5MG
- CAS:
- 383418-30-2
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