HEXAMETHYLPHOSPHORAMIDE 99% (C005B-056902)

General description

Hexamethylphosphoramide is a polar aprotic solvent.

Application

Hexamethylphosphoramide can be used as a solvent:

• For the conversion of carboxylate salt into esters by reacting with alkyl halides.
• To synthesize aryl thioethers via nucleophilic displacement of unactivated aryl halides by thiolate ions.
• To synthesize polyazomethines (PAZs) from dialdehyde and diamine via high-temperature solution polycondensation.

Molecular Weight: 179.20. Empirical Formula: C₆H₁₈N₃OP. linearFormula: [(CH₃)₂N]₃PO. vapor density: 6.18 (vs air). Quality Level: 200. vapor pressure: 0.07 mmHg ( 25 °C). Assay: 99%. refractive index: n20/D 1.459 (lit.). bp: 230-232 . °C/740 . mmHg (lit.). mp: 7 . °C (lit.). density: 1.03 . g/mL . at 25 . °C (lit.). SMILES string: CN(C)P(: O)(N(C)C)N(C)C. InChI: 1S/C6H18N3OP/c1-7(2)11(10,8(3)4)9(5)6/h1-6H3. InChI key: GNOIPBMMFNIUFM-UHFFFAOYSA-N. Pictograms: GHS05,GHS08. Signal Word: Danger. Hazard Statements: H314 - H340 - H350. Precautionary Statements: P202 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363. Hazard Classifications: Carc. 1B - Eye Dam. 1 - Muta. 1B - Skin Corr. 1C. Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects. WGK: WGK 3. Flash Point(F): 291.2 °F - closed cup. Flash Point(C): 144 °C - closed cup. Personal Protective Equipment: Eyeshields, Gloves, type ABEK (EN14387) respirator filter.