Name: HEMIN BIOXTRA FROM PORCINE >=97.0% (HPLC) (C005B-020588)
SKU: C005B-020588
Availability: OutOfStock

HEMIN BIOXTRA FROM PORCINE >=97.0% (HPLC) (C005B-020588)

Catalog No.

C005B-020588

Manufacturer No.

51280-5G

Manufacturer Name

Sigma-Aldrich

Quantity

Unit of Measure

Application Hemin is used for the following applications: To study bacterial strains and growth conditions Used in short-term colony assays (the culture medium consists of hemin along with other components) Cell transfections It may be used in

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Description
Specifications

Application

Hemin is used for the following applications:

To study bacterial strains and growth conditions
Used in short-term colony assays (the culture medium consists of hemin along with other components)
Cell transfections

It may be used in β-hematin formation assay for analyzing the inhibitory activity of MMV (Medicines for Malaria Venture) Malaria Box compounds against the formation of β-hematin.

Biochem/physiol Actions

Hemin, the oxidized version of heme, is an iron-containing prosthetic group for a diverse group of proteins. Free heme, which can be released from hemoglobin following hemolysis, is pro-inflammatory and contributes to iron-derived reactive oxygen species. Free hemin levels may be upregulated in various pathological conditions and can contribute to various inflammatory conditions including vascular disorders, renal failure, and immune-mediated disorders.

Hemin may be used to study the expression and represson of heme oxygenase 1 (HO-1) as well as the activity of HO-1. Hematin is the "X factor" required to grown Haemophilus influenzae.

Molecular Weight: 651.94. Empirical Formula: C₃₄H₃₂ClFeN₄O₄. biological source: Porcine. Quality Level: 200. product line: BioXtra. Assay: ≥. 96.0% (HPLC). form: powder or crystals. technique(s): tissue culture: suitable, transfection: suitable. storage temp.: 2-8Â°C. SMILES string: Cc1c(CCC(O): O)c2cc3c(CCC(O): O)c(C)c4cc5nc(cc6c(C)c(C: C)c(cc1n2)n6[Fe](Cl)n34)c(C: C)c5C. InChI: 1S/C34H34N4O4.ClH.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25. . /h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42). 1H. /q. . +3/p-3/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-. . . InChI key: BTIJJDXEELBZFS-HXFTUNQESA-K. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).