HARMALINE >=95%

Application

Reactant for preparation of:

• Acylated harmalines via Friedel-Crafts reaction
• Phenacyl derivatives of 1-methyl-7-methoxy-β-carbolines as central nervous system affectors
• Palladium harmaline DMSO chloro complex as anti-tumor agent

Natural product scaffold in preparation of:

• Trypanothione reductase inhibitors†

Biochem/physiol Actions

CNS stimulant; may act through NMDA receptors

Molecular Weight: 214.26. Empirical Formula: C₁₃H₁₄N₂O. Quality Level: 100. Assay: ≥. 95%. form: powder. drug control: regulated under CDSA - not available from Sigma-Aldrich Canada, stupéfiant (France). regulated under CDSA - not available from Sigma-Aldrich Canada . mp: 232-234 . °C (lit.). SMILES string: COc1ccc2c3CCN: C(C)c3[nH]c2c1. InChI: 1S/C13H14N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-4,7,15H,5-6H2,1-2H3. InChI key: RERZNCLIYCABFS-UHFFFAOYSA-N. Gene Information: human ... ADRA1A(148), ADRA1B(147), ADRA2A(150), ADRA2B(151), ADRA2C(152), ADRB1(153), ADRB2(154), CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133), DRD1(1812), DRD5(1816), HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR2C(3358), HTR3A(3359), HTR5A(3361), HTR6(3362), HTR7(3363), SLC6A2(6530), SLC6A4(6532), SLC9A2(6549), SLC9A5(6553)
rat ... Drd2(24318), Drd3(29238), Drd4(25432), Htr2a(29595), Maoa(29253), Maob(25750), Slc9a1(24782), Slc9a3(24784). Pictograms: GHS07,GHS08. Signal Word: Warning. Hazard Statements: H302 - H371. Precautionary Statements: P260 - P264 - P301 + P312 - P308 + P311 - P405 - P501. Hazard Classifications: Acute Tox. 4 Oral - STOT SE 2. Target Organs: Central nervous system. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).