HALOFUGINONE HYDROBROMIDE

General description

Halofuginone hydrobromide is a synthetic alkaloid derivative of febrifugine, used widely against coccidiosis in the poultry sector. It′s a specific collagen Type I inhibitor that antagonizes or inhibits the development of new blood vessels and hence can prevent intimal hyperplasia at a vascular anastomosis.

Application

The analytical standard can be used as follows:

• Multi-residue analysis of 11 coccidiostats in 60 feed samples by reversed phase-high performance liquid chromatography (RP-HPLC) combined with tandem mass spectrometry (MS/MS)
• Simultaneous determination of 15 allowed and banned coccidiostats in animal feed samples by liquid chromatography-tandem mass spectrometry method (LC-MS/MS)
• UHPLC-MS/MS method-based detection and measurement of 26 anticoccidials in surface and groundwater samples following their solid phase extraction (SPE)
• Analysis of 48 anti-microbial compounds in pig feed samples using LC combined with high-resolution mass spectrometry (HRMS)(4)Development of an LC-MS/MS method to determine 20 coccidiostats in different animal muscle samples

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Sigma-Aldrich Chemie GmbH

Molecular Weight: 495.59. Empirical Formula: C₁₆H₁₇BrClN₃O₃ · HBr. grade: analytical standard. Quality Level: 100. product line: VETRANAL^®. . shelf life: limited shelf life, expiry date on the label. technique(s): HPLC: suitable, gas chromatography (GC): suitable. application(s): forensics and toxicology
pharmaceutical (small molecule). format: neat. SMILES string: Br.O[C@@H]1CCCN[C@H]1CC(: O)CN2C: Nc3cc(Br)c(Cl)cc3C2: O. InChI: 1S/C16H17BrClN3O3.BrH/c17-11-6-13-10(5-12(11)18)16(24)21(8-20-13)7-9(22)4-14-15(23)2-1-3-19-14. /h5-6,8,14-15,19,23H,1-4,7H2. 1H/t14-,15+. /m0./s1. InChI key: SJUWEPZBTXEUMU-LDXVYITESA-N. Pictograms: GHS06,GHS09. Signal Word: Danger. Hazard Statements: H300 + H310 + H330 - H315 - H319 - H410. Precautionary Statements: P262 - P264 - P273 - P280 - P302 + P352 + P310 - P304 + P340 + P310. Hazard Classifications: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2. Storage Class Code: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.