GW438014A is a potent and selective NPY-Y5 receptor antagonist. GW438014A inhibits food intake and reduces body weight gain in obese rodents.In VivoGW438014A (10 mg/kg; i.p.; daily, for 7 d) inhibits spontaneous as well as overnight fasting-induced and NPY-induced feeding in rats and in food-deprived genetically obese ob/ob mice . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: obese ob/ob mice Dosage: 10 mg/kg Administration: intraperitoneal injection; daily, for 7 d Result: Decreased the rate of weight gain in both lean and obese rats.Form:Solid.
Specifications and Purity: ≥99%
Molecular Formula: C22H19N3O
Molecular Weight: 341.4
PubChem CID: 6918627
Isomeric SMILES: C1=CC=C(C=C1)CCN2C3=CC=CC=C3N=C2NC(=O)C4=CC=CC=C4
- UPC:
- 41114404
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- G648232-25mg
- CAS:
- 469861-49-2
- Product Size:
- 25mg
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