GST T2-2 RECOMBINANT RAT

Biochem/physiol Actions

Glutathione S-transferase theta 2 (Gstt2) is an enzyme that in rats is encoded by the Gstt2 gene. Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. The GSTs are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.

Storage and Stability

The enzyme should be used by the end-user customer within 1 year of receipt.

biological source: rat. Quality Level: 100. recombinant: expressed in E. coli. Assay: >. 95% (SDS-PAGE). form: frozen liquid. specific activity: 13.18 (using spectrophotometric determination of NADPH oxidation coupled to the glutathione peroxidase activity of GST T2-2 on cumene hydroperoxide (1.5 mM) in the presence of reduced glutathione (1 mM) in 100 mM NaPO4 (pH 7.0) at room temperature.). mol wt: 23 . kDa. concentration: 2.44 . mg/mL. storage temp.: −. 70°C. Gene Information: rat ... Gstt2(29487). Storage Class Code: 10 - Combustible liquids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.