GSK-A1 is a selective type III phosphatidylinositol 4-kinase PI4KA (PI4KIIIα) inhibitor with a pIC 50 of 8.5-9.8. GSK-A1 inhibits PtdIns(4,5)P2 resynthesis with an IC 50 of about 3 nM. GSK-A1 potently decreases the levels of PtdIns(4)P with a negligible effect on PtdIns(4,5)P2. GSK-A1 has the potential for anti-hepatitis C virus ( HCV ) researchForm:SolidIC50& Target:PI4KA 8.5-9.8 (pIC 50 ) PI4KB 7.2-7.7 (pIC 50 ) PI4K2A <5 (pIC 50 ) PI4K2B <5 (pIC 50 ).
Specifications and Purity: ≥98%
Molecular Formula: C29H27FN6O4S
Molecular Weight: 574.63
PubChem CID: 71116366
Isomeric SMILES: COC1=C(C=C(C=N1)C2=CC3=C(C=C2)N=C(N3C4=CC=C(C=C4)N5CCOCC5)N)S(=O)(=O)NC6=CC=CC=C6F
- UPC:
- 42172008
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- G651371-1mg
- CAS:
- 1416334-69-4
- Product Size:
- 1mg
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