InformationGSK-114 is a selective inhibitor of TNNI3 Interacting Kinase (TNNI3K) with IC50 of 25 nM. GSK-114 shows significant bias for TNNI3K over B-Raf with IC50 of 1000 nM, exceptional broad spectrum kinase selectivity and adequate oral exposure to enable its use in cellular and in vivo studies.
Specifications and Purity: ≥98%
Molecular Formula: C19H23N5O4S
Molecular Weight: 417.5
PubChem CID: 52933152
Isomeric SMILES: CNS(=O)(=O)C1=CC(=C(C=C1)N(C)C)NC2=NC=NC3=CC(=C(C=C32)OC)OC
- UPC:
- 41116106
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- G412389-5mg
- CAS:
- 1301761-96-5
- Product Size:
- 5mg
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