Biochem/physiol Actions GS-6201 (CVT-6883) is a potent and selective A2B adenosine receptor (A2BAdoR) antagonist. GS-6201 reduces caspase-1 activity in the heart and leads to a more favorable cardiac remodeling in a mouse model of non-reperfused
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GS-6201 (CVT-6883) is a potent and selective A2B adenosine receptor (A2BAdoR) antagonist. GS-6201 reduces caspase-1 activity in the heart and leads to a more favorable cardiac remodeling in a mouse model of non-reperfused myocardial infarction. Also GS-6201 attenuated vascular remodeling and hypertension in mouse model.
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